Invasive Mold Infections After Chimeric Antigen Receptor–Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis

Resource type
Journal Article
Authors/contributors
Title
Invasive Mold Infections After Chimeric Antigen Receptor–Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis
Abstract
Data on invasive mold infections (IMIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) therapy are limited. We describe 2 patients with post–CAR-T-cell IMI (Fusarium, Mucorales) and review the published literature. We propose strategies to prevent IMIs in patients, based on the IMI rate and presence of neutropenia or steroid use.
Publication
Clinical Infectious Diseases
Date
July 27, 2020
Volume
71
Issue
3
Pages
672-676
Journal Abbr
Clinical Infectious Diseases
Accessed
12/10/20, 9:25 AM
ISSN
1058-4838
Short Title
Invasive Mold Infections After Chimeric Antigen Receptor–Modified T-Cell Therapy
Library Catalog
Silverchair
Citation
Haidar, G., Dorritie, K., Farah, R., Bogdanovich, T., Nguyen, M. H., & Samanta, P. (2020). Invasive Mold Infections After Chimeric Antigen Receptor–Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis. Clinical Infectious Diseases, 71(3), 672–676. https://doi.org/10.1093/cid/ciz1127
HEME-ONC AND CELLULAR THERAPIES