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Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation
Resource type
Journal Article
Authors/contributors
- Marty, Francisco M. (Author)
- Ljungman, Per (Author)
- Chemaly, Roy F. (Author)
- Maertens, Johan (Author)
- Dadwal, Sanjeet S. (Author)
- Duarte, Rafael F. (Author)
- Haider, Shariq (Author)
- Ullmann, Andrew J. (Author)
- Katayama, Yuta (Author)
- Brown, Janice (Author)
- Mullane, Kathleen M. (Author)
- Boeckh, Michael (Author)
- Blumberg, Emily A. (Author)
- Einsele, Hermann (Author)
- Snydman, David R. (Author)
- Kanda, Yoshinobu (Author)
- DiNubile, Mark J. (Author)
- Teal, Valerie L. (Author)
- Wan, Hong (Author)
- Murata, Yoshihiko (Author)
- Kartsonis, Nicholas A. (Author)
- Leavitt, Randi Y. (Author)
- Badshah, Cyrus (Author)
Title
Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation
Abstract
CMV infection is a common complication in patients undergoing hematopoietic-cell transplantation. The incidence of CMV infection was 23 percentage points lower with prophylactic letermovir, a CMV–terminase complex inhibitor, than with placebo, with only low-level toxic effects.
Publication
New England Journal of Medicine
Date
December 21, 2017
Volume
377
Issue
25
Pages
2433-2444
Accessed
12/13/18, 6:14 PM
ISSN
0028-4793
Library Catalog
Taylor and Francis+NEJM
Extra
PMID: 29211658
Citation
Marty, F. M., Ljungman, P., Chemaly, R. F., Maertens, J., Dadwal, S. S., Duarte, R. F., Haider, S., Ullmann, A. J., Katayama, Y., Brown, J., Mullane, K. M., Boeckh, M., Blumberg, E. A., Einsele, H., Snydman, D. R., Kanda, Y., DiNubile, M. J., Teal, V. L., Wan, H., … Badshah, C. (2017). Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation. New England Journal of Medicine, 377(25), 2433–2444. https://doi.org/10.1056/NEJMoa1706640
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