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Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms
Resource type
Journal Article
Authors/contributors
- Ghani, Rohma (Author)
- Mullish, Benjamin H. (Author)
- McDonald, Julie A. K. (Author)
- Ghazy, Anan (Author)
- Williams, Horace R. T. (Author)
- Brannigan, Eimear T. (Author)
- Mookerjee, Siddharth (Author)
- Satta, Giovanni (Author)
- Gilchrist, Mark (Author)
- Duncan, Neill (Author)
- Corbett, Richard (Author)
- Innes, Andrew J. (Author)
- Pavlů, Jiří (Author)
- Thursz, Mark R. (Author)
- Davies, Frances (Author)
- Marchesi, Julian R. (Author)
Title
Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms
Abstract
Fecal microbiota transplantation (FMT) yields variable intestinal decolonization results for multidrug-resistant organisms (MDROs). This study showed significant reductions in antibiotic duration, bacteremia, and length of stay in 20 patients colonized/infected with MDRO receiving FMT (compared with pre-FMT history, and a matched group not receiving FMT), despite modest decolonization rates.
Publication
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Date
2021-04-26
Volume
72
Issue
8
Pages
1444-1447
Journal Abbr
Clin Infect Dis
ISSN
1537-6591
Short Title
Disease Prevention Not Decolonization
Language
eng
Library Catalog
PubMed
Extra
PMID: 32681643
PMCID: PMC8075030
Citation
Ghani, R., Mullish, B. H., McDonald, J. A. K., Ghazy, A., Williams, H. R. T., Brannigan, E. T., Mookerjee, S., Satta, G., Gilchrist, M., Duncan, N., Corbett, R., Innes, A. J., Pavlů, J., Thursz, M. R., Davies, F., & Marchesi, J. R. (2021). Disease Prevention Not Decolonization: A Model for Fecal Microbiota Transplantation in Patients Colonized With Multidrug-resistant Organisms. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 72(8), 1444–1447. https://doi.org/10.1093/cid/ciaa948
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