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Management of Mucorales Infections in Transplant Patients

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Resource type
Book Section
Authors/contributors
Title
Management of Mucorales Infections in Transplant Patients
Abstract
Infections due to Mucorales fungi in hematopoietic stem cell transplantation (HSCT) and solid organ transplant (SOT) recipients may be increasing. Disease is severe and rapidly progressive and carries high mortality. Both the prevalence and species epidemiology vary with geography. Rhizopus species is the most common pathogen followed by Mucor species. Risk factors in SOT patients include renal failure, diabetes mellitus, and immunosuppression to prevent rejection. Additional risks in HSCT patients include corticosteroid use, neutropenia, iron overload, newer immunomodulating therapies, and graft-versus-host disease Breakthrough mucormycosis has occurred in patients receiving voriconazole and caspofungin as well as with posaconazole oral solution. Outbreaks of infection occur.
Book Title
Emerging Transplant Infections
Date
2021
Publisher
Springer International Publishing
Place
Cham
Pages
1109-1138
ISBN
978-3-030-01751-4
URL
http://link.springer.com/10.1007/978-3-030-01751-4_45-1
Accessed
10/23/21, 9:33 AM
Language
en
Library Catalog
DOI.org (Crossref)
Extra
DOI: 10.1007/978-3-030-01751-4_45-1
Citation
Chen, S. C.-A., & Slavin, M. A. (2021). Management of Mucorales Infections in Transplant Patients. In M. I. Morris, C. N. Kotton, & C. Wolfe (Eds.), Emerging Transplant Infections (pp. 1109–1138). Springer International Publishing. https://doi.org/10.1007/978-3-030-01751-4_45-1
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https://www.transplantid.net/RN6MPJXZ