Vaccine schedule recommendations and updates for patients with hematologic malignancy post-hematopoietic cell transplant or CAR T-cell therapy

Resource type
Journal Article
Authors/contributors
Title
Vaccine schedule recommendations and updates for patients with hematologic malignancy post-hematopoietic cell transplant or CAR T-cell therapy
Abstract
Revaccination after receipt of a hematopoietic cell transplant (HCT) or cellular therapies is a pillar of patient supportive care, with the potential to reduce morbidity and mortality linked to vaccine-preventable infections. This review synthesizes national, international, and expert consensus vaccination schedules post-HCT and presents evidence regarding the efficacy of newer vaccine formulations for pneumococcus, recombinant zoster vaccine, and coronavirus disease 2019 in patients with hematological malignancy. Revaccination post-cellular therapies are less well defined. This review highlights important considerations around poor vaccine response, seroprevalence preservation after cellular therapies, and the optimal timing of revaccination. Future research should assess the immunogenicity and real-world effectiveness of new vaccine formulations and/or vaccine schedules in patients post-HCT and cellular therapy, including analysis of vaccine response that relates to the target of cellular therapies.
Publication
Transplant Infectious Disease
Volume
n/a
Issue
n/a
Pages
e14109
Accessed
9/2/23, 3:38 PM
ISSN
1399-3062
Language
en
Library Catalog
Wiley Online Library
License
© 2023 The Authors. Transplant Infectious Disease published by Wiley Periodicals LLC.
Citation
Reynolds, G., Hall, V. G., & Teh, B. W. (n.d.). Vaccine schedule recommendations and updates for patients with hematologic malignancy post-hematopoietic cell transplant or CAR T-cell therapy. Transplant Infectious Disease, n/a(n/a), e14109. https://doi.org/10.1111/tid.14109
PREVENTION
HEME-ONC AND CELLULAR THERAPIES